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Genomic analysis of the endosomal sorting required for transport complex III pathway genes as therapeutic and prognostic biomarkers for endometrial carcinoma

9 Aug 2022

Abstract excerpt

Background: The genes involved in the endosomal sorting required for transport complex (ESCRT)-III pathway is a protective mechanism that delays cell death by repairing damaged plasma membranes. We aimed to evaluate if targeting ESCRT-III genes may be used as biomarkers for predicting the clinical outcomes of endometrial carcinoma (EC). Methods: Transcriptome RNA sequence (RNA-seq) data and genomic information of...

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PMID: 36237250
DOI: 10.21037/tcr-22-660

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