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Article

Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses

2020-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Molecular details of how endocytosis contributes to oncogenesis remain elusive. Our in silico analysis of colorectal cancer (CRC) patients revealed stage-dependent alterations in the expression of 113 endocytosis-related genes. Among them transcription of the Endosomal Sorting Complex Required for Transport (ESCRT)-I component VPS37B was decreased in the advanced stages of CRC. Expression of o...

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Identifiers and source

Literature Corpus work
4287142b-12aa-5003-8ce1-00d9b8716a7f
DOI
10.1101/2020.07.02.183954
Open publication

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Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responsesDOI 10.1101/2020.07.02.183954
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