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Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back Signaling

2024-10-16

Abstract excerpt

<h4>Summary</h4> Neuronal heterogeneity is a defining feature of the developing mammalian brain, but the mechanisms regulating the diversification of closely related cell types remain elusive. In this study, we investigated the heterogeneity of dentate gyrus (DG) granule cells (GCs) and the influence of a psychosis associated V 321 L mutation in Neuregulin1 (Nrg1) on GC subtype composition. Using morpho-electric...

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Literature Corpus work
bdb4cb31-5892-53fa-a053-2d07d62b5048
DOI
10.1101/2024.10.15.618334
Open publication

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Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back SignalingDOI 10.1101/2024.10.15.618334
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