Article

Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer

2022-12-10

Abstract excerpt

Advanced prostate cancer patients initially respond to hormone therapy, be it in the form of androgen deprivation therapy or second-generation hormone therapies, such as abiraterone acetate or enzalutamide. However, most men with prostate cancer eventually develop hormone therapy resistance. This resistance emerges in several ways, such as through genetic mutations, epigenetic mechanisms, or through non-genetic pa...

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Literature Corpus work: bdaf4508-8f42-5b16-bfd1-4b066ee28c73
DOI: 10.1101/2022.12.06.516625

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