Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional and epigenetic reprogramming, lineage plasticity and therapy resistance in prostate cancer

13 Jun 2025

Abstract excerpt

Prostate cancer is the most commonly diagnosed and the second-leading cause of cancer-related mortality in men worldwide, especially in Western counties. Therapeutic resistance of prostate cancer remains a major challenge in modern oncology, necessitating new scientific understanding of the disease and devising new targeting strategies. This review examines the intricate relationship between transcriptional and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41738031
DOI: 10.1016/j.jncc.2025.06.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional and epigenetic reprogramming, lineage plasticity and therapy resistance in prostate cancerPMID 41738031Read ↗

Phenotypic Plasticity - Alternate Transcriptional Programs Driving Treatment Resistant Prostate CancerSemantic proximity Read ↗

Dynamics of Cellular Plasticity in Prostate Cancer ProgressionSemantic proximity Read ↗

Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolutionSemantic proximity Read ↗

Prostate cancer stem cell dynamics in the evolution of drug resistanceSemantic proximity Read ↗

Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistanceSemantic proximity Read ↗

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancerSemantic proximity Read ↗

Lineage Plasticity and Stemness Phenotypes in Prostate Cancer: Harnessing the Power of Integrated “Omics” Approaches to Explore Measurable MetricsSemantic proximity Read ↗

The Role of Lineage Plasticity in Prostate Cancer Therapy ResistanceSemantic proximity Read ↗

The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage PlasticitySemantic proximity Read ↗

Cellular plasticity and the neuroendocrine phenotype in prostate cancer.Semantic proximity Read ↗

Integrated single-cell transcriptomic analyses identify a novel lineage plasticity-related cancer cell type involved in prostate cancer progressionSemantic proximity Read ↗

LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.