Article

Targeting FSP1 triggers ferroptosis in lung cancer

2025-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Pre-clinical and clinical studies have demonstrated how dietary antioxidants or mutations activating antioxidant metabolism promote cancer, highlighting a central role oxidative stress in tumorigenesis. However, it is unclear if oxidative stress ultimately increases to a point of cell death. Emerging evidence indicates that cancer cells are susceptible to ferroptosis, a form of cell death trigge...

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Literature Corpus work: bd233842-0941-5f5a-ae90-5cc2de193d43
DOI: 10.1101/2025.08.07.668766

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