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Article

IRAK-M Regulates Proliferative and Invasive Phenotypes of Lung Fibroblasts.

Inflammation - 1 Apr 2023

Zheng Zhoude, Li Jia, Cui Ye, Wang Wei, Zhang Mingqiang, Zhang Youming, Bai Yan, Ying Sun, Gao Jinming

Abstract excerpt

Lung fibroblasts play an important role in subepithelial fibrosis, one feature for airway remodeling. IL-1 receptor-associated kinase (IRAK)-M was shown to involve fibrosis formation in airways and lung through regulation of inflammatory responses. IRAK-M is expressed by lung fibroblasts, whether IRAK-M has direct impact on lung fibroblasts remains unclear. In this investigation, we evaluated in vitro effect of...

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PMID: 36577924
DOI: 10.1007/s10753-022-01772-4

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