Article

Heat shock factor 2 positively regulates oncogenic herpesvirus gene expression by remodeling the chromatin landscape

2024-11-23

Abstract excerpt

Human gamma-herpesviruses, Kaposi’s sarcoma herpesvirus (KSHV) and Epstein-Barr virus (EBV) are causally associated to a wide range of cancers. While the default infection program for these viruses is latent, sporadic lytic reactivation supports virus dissemination and oncogenesis. Despite its relevance, the repertoire of host factors governing the transition from latent to lytic phase is not yet complete, leaving...

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Literature Corpus work: bcc64a17-e091-5237-a339-4a6671617f2b
DOI: 10.1101/2024.11.22.624798

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