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Highly pathogenic avian influenza H5N1: history, current situation, and outlook

27 Mar 2025

Abstract excerpt

The H5N1 avian panzootic has resulted in cross-species transmission to birds and mammals, causing outbreaks in wildlife, poultry, and US dairy cattle with a range of host-dependent pathogenic outcomes. Although no human-to-human transmission has been observed, the rising number of zoonotic human cases creates opportunities for adaptive mutation or reassortment. This Gem explores the history, evolution, virology,...

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PMID: 40145745
DOI: 10.1128/jvi.02209-24

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