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Article

Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies

1 Jan 2025

Abstract excerpt

• Phylogenetic analysis of genotype B3.13 and D1.1 across the species • Mutations on the receptor binding sites related to receptor preferring • Host adaptability differences between B3.13 and D1.1 • Antivirals resistance mutations emergence of genotype B3.13 and D1.1 The recent report of the first fatality associated with infection by influenza virus H5N1 clade 2.3.4.4b, identified as genotype D1.1, which is...

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Identifiers

PMID: 40177627
DOI: 10.1016/j.crmicr.2025.100377

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