Article

MFAP5 Drives Elastic Fiber Disorganization to Promote Pulmonary Fibrosis

2025-12-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Elastic fibers (EF) disorganization contributes to increased tissue stiffness and impaired lung function in pulmonary fibrosis (PF). However, the complex structural features of EF are difficult to capture using conventional histology. Moreover, the molecular mechanisms governing EF homeostasis during fibrosis remain poorly understood. <h4>METHODS</h4> A high-dimensional Ela...

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Literature Corpus work: bc8d5c12-d5ab-5723-8040-cb87ee86ffef
DOI: 10.64898/2025.12.09.693350

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