Article

Adipocyte-specific modulation of KLF14 expression in mice leads to sex-dependent impacts in adiposity and lipid metabolism

2021-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies identified single nucleotide polymorphisms on chromosome 7 upstream of KLF14 to be associated with metabolic syndrome traits and increased risk for Type 2 Diabetes (T2D). The associations were more significant in women than in men. The risk allele carriers expressed lower levels of the transcription factor KLF14 in adipose tissues than non-risk allele carriers. T...

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Literature Corpus work: bc7d8858-fd9d-55c9-92ec-b96485c85b0b
DOI: 10.1101/2021.09.15.460489

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