Article

Male mouse strain variation reveals divergent phenotypes for extrinsic and intrinsic reward motivation

2026-08-15

Abstract excerpt

Motivational deficit is a prevalent symptom across a wide range of neurodegenerative and neuropsychiatric disorders. Despite its clinical importance, first-line treatments for these disorders fail to effectively treat this symptom domain. In animal models, motivation is typically assessed in the context of extrinsic reward, where reward is delivered for completing an effortful action. However, many motivated behav...

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Literature Corpus work: fae2aec1-a5c9-5540-afdb-22114d966856
DOI: 10.64898/2026.08.11.743966

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