Article
Glutamate and dopamine transmission from midbrain dopamine neurons share similar release properties but are differentially affected by cocaine.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Feb 2014
Adrover Martín F, Shin Jung Hoon, Alvarez Veronica A
Abstract excerpt
Synaptic transmission between ventral tegmental area and nucleus accumbens (NAc) is critically involved in reward-motivated behaviors and thought to be altered in addiction. In addition to dopamine (DA), glutamate is packaged and released by a subset of mesolimbic DA neurons, eliciting EPSCs onto medium spiny neurons in NAc. Little is known about the properties and modulation of glutamate release from DA midbrain...
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