Article

The Isolation of Pyrroloformamide Congeners and Characterization of Its Biosynthetic Gene Cluster from Streptomyces sp. CB02980 Revealed a Unified Mechanism for Dithiolopyrrolone Biosynthesis

2019-11-07

Abstract excerpt

Dithiolopyrrolones are microbial natural products containing a disulfide or thiosulfonate bridge embedded in a unique bicyclic structure. In the current study, two new dithiolopyrrolones, pyrroloformamide C ( 3 ) and pyrroloformamide D ( 4 ), were isolated from Streptomyces sp. CB02980, together with the known pyrroloformamides 1 and 2 . The biosynthetic gene cluster for pyrroloformamides was identified from...

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Literature Corpus work: bbdde353-52a6-597f-ade9-9ac95bb0e317
DOI: 10.26434/chemrxiv.10208717.v1

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The Isolation of Pyrroloformamide Congeners and Characterization of Its Biosynthetic Gene Cluster from Streptomyces sp. CB02980 Revealed a Unified Mechanism for Dithiolopyrrolone BiosynthesisDOI 10.26434/chemrxiv.10208717.v1Read

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