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Novel elasticity measurement techniques reveal that the <i>C. elegans</i> cuticle is required for physical integrity with age

2021-10-05

Abstract excerpt

Changes in biomechanical properties have profound impacts on human health. C. elegans might serve as a model for studying the molecular genetics of mammalian tissue decline. Previously, we found that collagens are required for insulin signaling mutants’ long lifespan and that overexpression of specific collagens extends wild-type lifespan. However, whether these effects on lifespan are due to mechanical changes d...

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Literature Corpus work
bba89b78-d931-5c85-a1c9-d7633e65b158
DOI
10.1101/2021.10.04.463135
Open publication

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Novel elasticity measurement techniques reveal that the <i>C. elegans</i> cuticle is required for physical integrity with ageDOI 10.1101/2021.10.04.463135
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