Article

Non-Coding and Loss-of-Function Coding Variants in <i>TET2</i> are Associated with Multiple Neurodegenerative Diseases

2019-09-16

Abstract excerpt

<h4>ABSTRACT</h4> We conducted genome sequencing to search for rare variation contributing to early onset Alzheimer’s disease (EOAD) and frontotemporal dementia (FTD). Discovery analysis was conducted on 493 cases and 671 controls of European ancestry. Burden testing for rare variation associated with disease was conducted using filters based on variant rarity (less than 1 in 10,000 or private), computational pre...

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Literature Corpus work: bb934319-856d-5728-9c26-2c21d9b3bd3b
DOI: 10.1101/759621

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