Article

Expansion load: recessive mutations and the role of standing genetic variation

2014-11-18

Abstract excerpt

Expanding populations incur a mutation burden – the so-called expansion load. Previous studies of expansion load have focused on co-dominant mutations. An important consequence of this assumption is that expansion load stems exclusively from the accumulation of new mutations occurring in individuals living at the wave front. Using individual-based simulations we study here the dynamics of standing genetic variatio...

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Literature Corpus work: f9b6088e-2350-5191-aa4d-8ba93baf25a3
DOI: 10.1101/011593

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