Article

Pharmacogenetics of efavirenz exposure in cervicovaginal fluid during pregnancy and postpartum

2023-10-15

Abstract excerpt

<h4>Objectives</h4> Adequate antiretroviral drug distribution into the female genital tract (FGT) could play an important role in reducing the risk of heterosexual and mother-to-child transmission of HIV. In this study, we investigated the combined influence of pregnancy and genetic polymorphisms on efavirenz pharmacokinetics in cervicovaginal fluid (CVF) of women receiving antiretroviral therapy. <h4>Methods</h4>...

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Literature Corpus work: bb17ce90-8aeb-51c4-83a5-e6a9db9d8551
DOI: 10.1101/2023.10.15.23297046

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