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Article

Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV

23 Jan 2018

Abstract excerpt

OBJECTIVE: To evaluate dolutegravir pharmacokinetics during pregnancy compared with postpartum and in infant washout samples after delivery. DESIGN: Ongoing, nonrandomized, open-label, parallel-group, multicenter phase-IV prospective study of antiretroviral pharmacokinetics in HIV-infected pregnant women and infants. METHODS: Intensive steady-state 24 h pharmacokinetic profiles after dolutegravir 50 mg once-daily...

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PMID: 29369162
DOI: 10.1097/qad.0000000000001755

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