Article
Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.
AIDS research and therapy - 31 Mar 2023
Buzibye Allan, Wools-Kaloustian Kara, Olagunju Adeniyi, Twinomuhwezi Ellon, Yiannoutsos Constantin, Owen Andrew, Neary Megan, Matovu Joshua, Banturaki Grace, Castelnuovo Barbara, Lamorde Mohammed, Khoo Saye, Waitt Catriona, Kiragga Agnes
Abstract excerpt
BACKGROUND: We investigated the association between CYP2B6 polymorphisms and efavirenz drug resistance among women living with HIV who started on antiretroviral therapy during pregnancy and with high viremia during post-partum. METHODS: This was a cross-sectional study of women with viral loads greater than 1000 copies/ml who were at least 6 weeks postpartum. Sanger sequencing was used to detect resistant...
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