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Article

Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens.

PLoS neglected tropical diseases - 1 Apr 2014

Parobek Christian M, Bailey Jeffrey A, Hathaway Nicholas J, Socheat Duong, Rogers William O, Juliano Jonathan J

Abstract excerpt

Although Plasmodium vivax is a leading cause of malaria around the world, only a handful of vivax antigens are being studied for vaccine development. Here, we investigated genetic signatures of selection and geospatial genetic diversity of two leading vivax vaccine antigens--Plasmodium vivax merozoite surface protein 1 (pvmsp-1) and Plasmodium vivax circumsporozoite protein (pvcsp). Using scalable next-generation...

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Identifiers

PMID: 24743266
DOI: 10.1371/journal.pntd.0002796
PMCID: PMC3990511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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