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Targeting LRP1 to Impede Malignant Progression in Glioblastoma: Involving the SP1-Mediated PI3K/AKT Pathway

2025-12-22

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Lactylation is a new epigenetic modification. Recent research has revealed that it is an indispensable in tumor progression and the immune microenvironment. However, its role in proliferation and invasion within glioblastoma remains unclear. <bold>Methods:</bold> Using data from TCGA (for GBM) and GTEx (for normal tissues), we screened for genes with potent...

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Literature Corpus work
bae63345-6d39-53b9-8fea-6e74173cb450
DOI
10.21203/rs.3.rs-8197635/v1
Open publication

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Targeting LRP1 to Impede Malignant Progression in Glioblastoma: Involving the SP1-Mediated PI3K/AKT PathwayDOI 10.21203/rs.3.rs-8197635/v1
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