Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated single-cell and bulk RNA-sequencing data reveal molecular subtypes based on lactylation-related genes and prognosis and therapeutic response in glioma

1 May 2024

Abstract excerpt

Objectives: Glioma, the most common and aggressive form of brain cancer, possesses a complex biology, which makes elucidating its underlying mechanisms and developing effective treatment strategies challenging. Lactylation is a recently discovered post-translational modification and has emerged as a novel research target to understand its role in various biological processes and diseases. Herein, we explored the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38765164
DOI: 10.1016/j.heliyon.2024.e30726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated single-cell and bulk RNA-sequencing data reveal molecular subtypes based on lactylation-related genes and prognosis and therapeutic response in gliomaPMID 38765164Read ↗

Lactylation-related gene signatures identify glioma molecular subtypes with prognostic, immunological, and therapeutic implicationsSemantic proximity Read ↗

Integrated single-cell and bulk RNA-sequencing data reveal prognosis and therapeutic response in low-grade glioma based on hypoxia-lactylation related genesSemantic proximity Read ↗

Unlocking the secret of glioblastoma multiforme: the role of lactylation in tumor progression, drug resistance and immune microenvironmentSemantic proximity Read ↗

Identification of a lactylation-related gene signature to characterize subtypes of hepatocellular carcinoma using bulk sequencing dataSemantic proximity Read ↗

Construction of a prognostic model using lactylation-related genes for predicting the prognosis of glioma patients.Semantic proximity Read ↗

Integrated analysis of single-cell RNA-seq and spatial transcriptomics to identify the lactylation-related protein TUBB2A as a potential biomarker for glioblastoma in cancer cells by machine learningSemantic proximity Read ↗

A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancerSemantic proximity Read ↗

Identification of a Novel Disulfideptosis-Related LncRNA Signature and Integrative Analyses in Patients with GliomasSemantic proximity Read ↗

M2 TAM-related risk signature based on single-cell and bulk RNA sequencing to evaluate tumor immune microenvironment and predict prognosis in gliomaSemantic proximity Read ↗

Identification and Validation of Prognostic Genes Related to Histone Lactylation Modification in Glioblastoma: An Integrated Analysis of Transcriptome and Single-cell RNA SequencingSemantic proximity Read ↗

Single-cell transcriptome-based multilayer network biomarker for predicting prognosis and therapeutic response of gliomasSemantic proximity Read ↗

Lactylation-related gene signature for prognostic prediction and immune infiltration analysis in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.