Article
Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave Like Fibroblasts, Rather than Epithelial Cells, in Experimental HCMV Infection Studies
2023-10-28
Abstract excerpt
Human cytomegalovirus (HCMV) has a broad cellular tropism and epithelial cells are important physiological targets during infection. The retinal pigment epithelial cell line ARPE-19 has been used to model HCMV infection in epithelial cells for decades and remains a commonly used cell-type for studying viral entry, replication, and the cellular response to infection. We previously found that ARPE-19 cells, despite...
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Identifiers and source
- Literature Corpus work
- bad9cc70-74fd-51a6-a1bf-6ed6a1adf8a6
- DOI
- 10.1101/2023.10.27.564463
