Article

Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

2020-07-10

Abstract excerpt

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), which is the cause of a present global pandemic, infects human lung alveolar cells (hACs). Characterising the pathogenesis is crucial for developing vaccines and therapeutics. However, the lack of models mirroring the cellular physiology and pathology of hACs limits the study. Here, we develop a feeder-free, long-term three-dimensional (3D) culture tech...

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Literature Corpus work: e3e4bd49-feea-5857-b3d8-0d46e3f89b55
DOI: 10.1101/2020.07.10.194498

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