Article

Renin is critical for Renin Lineage Cell Plasticity and Migration in experimental crescentic Glomerulonephritis

2026-02-14

Abstract excerpt

<h4>Key Points</h4> Renin deficiency in renin-lineage cells worsened crescentic injury and impaired cell migration, revealing a protective role for renin in crescentic glomerulonephritis. Loss of renin shifted renin-lineage cells signaling toward interferon/STAT1-driven Renin-lineage cell ablation in crescentic glomerulonephritis induced a less inflammatory disease time-course. <h4>Background</h4> The adult juxt...

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Literature Corpus work: ba8e2e22-ca5c-511c-a336-d3df30eac235
DOI: 10.64898/2026.02.11.705281

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