Article

Neonatal-derived IL-17 producing dermal γδ T cells are required to prevent spontaneous atopic dermatitis

2019-06-28

Abstract excerpt

<h4>ABSTRACT</h4> Atopic Dermatitis (AD) is a T cell-mediated chronic skin disease and is associated with altered skin barrier integrity. Infants with mutations in genes involved in tissue barrier fitness are predisposed towards inflammatory diseases, but most do not develop or sustain the diseases, suggesting that there exist regulatory immune mechanisms to repair tissues and/or prevent aberrant inflammation. Th...

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Literature Corpus work: 99a70605-d952-5f20-b702-13ab02814fd4
DOI: 10.1101/686576

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