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Article

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

2016-12-02

Abstract excerpt

Abstract Chronic infections including tuberculosis, hepatitis C, and HIV are estimated to affect over a third of the world's population and are associated with significant health implications including bone marrow suppression and an increased risk for cancer (Jian et al., 2014; Ramos-Casals et al., 2003; Scadden et al., 1989). Pancytopenia, a suppression of blood counts across multiple lineages, can affect as many...

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Literature Corpus work
ba6ad615-af57-5a58-be32-d65dcaa352a0
DOI
10.1182/blood.v128.22.732.732
Open publication

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Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal DifferentiationDOI 10.1182/blood.v128.22.732.732
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