Article
Isolation and Functional Characterization of Myeloid-Derived Suppressor Cells in Infections Under High Containment.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Kotze Leigh A, Leukes Vinzeigh N, Du Plessis Nelita
Abstract excerpt
The current absence of markers unique to MDSC, particularly those expanded during human infection, necessitate concurrent demonstration of their suppressive capacity to ensure unequivocal identification. This is further complicated by the array of heterogeneous markers used to characterize MDSC in various conditions and models. Standardization of phenotypic and functional characterization, as well as isolation,...
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