Article

Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging

2021-11-25

Abstract excerpt

The etiology of cognitive dysfunction associated with Alzheimer’s disease (AD) and dementia is multifactorial. Yet, mechanistic interactions among key neurobiological factors linked to AD pathology are unclear. This study tested the effect of interactions between cerebrovascular function, individual genotype, and structural brain pathology on response inhibition performance, an early and sensitive indicator of cog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ba60e0a1-b548-5b45-8263-06915b8603a4
DOI: 10.1101/2021.11.22.469615

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with agingDOI 10.1101/2021.11.22.469615Read

Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging.Semantic proximity Read

APOE4 carriers resistant to cognitive decline show unique relationships between cerebrovascular response to exercise and dual-task cognitive-balance performanceSemantic proximity Read

Dementia Risk and Dynamic Response to Exercise: A non-randomized clinical trialSemantic proximity Read

Cerebral Vasoreactivity, Apolipoprotein E, and the Risk of Dementia: A Population-Based Study.Semantic proximity Read

APOE genotype modifies the association between central arterial stiffening and cognition in older adults.Semantic proximity Read

Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.Semantic proximity Read

Dementia Risk and Dynamic Response to Exercise: Methodology for an Acute Exericise Clinical TrialSemantic proximity Read

Cerebrovascular regulation dynamics and Alzheimer's neuroimaging phenotypes.Semantic proximity Read

APOE4 carriers display loss of anticipatory cerebrovascular regulation across the Alzheimer's disease continuum.Semantic proximity Read

Distinct effects of amyloid and tau deposition on eigenvector centrality during hippocampal down-regulation: a real-time fMRI virtual reality closed-loop neurofeedback study with CSF biomarkersSemantic proximity Read

Stressor-evoked brain activity, cardiovascular reactivity, and subclinical atherosclerosis in midlife adultsSemantic proximity Read

APOE4 carriers display loss of anticipatory cerebral vascular regulation over AD progressionSemantic proximity Read