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Article

Cerebrovascular regulation dynamics and Alzheimer's neuroimaging phenotypes.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2026

Tsiknia Amaryllis A, Terner Jamie A, Tsokolas Zoe E, Shin Dae C, Joe Elizabeth B, Conti Peter S, Lepping Rebecca J, Kelley Brendan J, Zhang Rong, Billinger Sandra A, Chui Helena C, Marmarelis Vasilis Z, Braskie Meredith N

Abstract excerpt

INTRODUCTION: Cerebrovascular dysfunction may contribute to Alzheimer's disease (AD) pathogenesis. We examined how novel cerebral hemodynamic markers relate to neuroimaging phenotypes associated with AD dementia in cognitively impaired and unimpaired older adults. METHODS: Statistical hemodynamic indices were computed for each participant from stochastic dynamic models relating resting-state spontaneous arterial...

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Identifiers

PMID: 41685442
DOI: 10.1002/alz.71146
PMCID: PMC12902799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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