Article

Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic and Chemogenic Manipulations

2021-04-09

Abstract excerpt

The melanin concentrating hormone (MCH) system is involved in numerous functions including energy homeostasis, food intake, sleep, stress, mood, aggression, reward, maternal behavior, social behavior, and cognition. MCH acts on a G protein-coupled receptor MCHR1, which expresses ubiquitously in the brain and localizes to neuronal primary cilia. Cilia act as cells’ antennas and play crucial roles in cell signaling...

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Literature Corpus work: ba5db434-38b0-5187-a4d8-97573568e448
DOI: 10.1101/2021.04.07.438846

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