Article
Neuronal Cilia: Another Player in the Melanocortin System.
Trends in molecular medicine - 1 Apr 2018
Varela Luis, Horvath Tamas L
Abstract excerpt
Melanocortin receptors play crucial roles in multiple physiological processes. Melanocortin receptor 4 (MC4R) is expressed in key brain regions, and MC4R gene mutations can cause severe obesity. However, the cellular biology of MC4R is less well understood owing to the lack of reliable methods to visualize its location. Recently, Siljee and colleagues localized MC4R to the cilia of the neurons within the...
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