Article

High prevalence of loss of Y chromosome in the spermatozoa of young cancer survivors

2026-03-23

Abstract excerpt

Cancer-related genomic instability (GI) may cause genetic alterations in spermatozoa, implying health issues not only in cancer survivors, but also in their children [1, 2]. We therefore studied Loss of Y chromosome (LOY), considered as hallmark of GI [3-15], in spermatozoa and blood from survivors of childhood and testicular cancer (CC, TC), and controls (CTRL). We found that LOY was statistically significantly m...

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Literature Corpus work: ba59e269-dde5-5237-9638-107899e66711
DOI: 10.64898/2026.03.20.26348822

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