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Association between loss of Y chromosome and poor prognosis in male head and neck squamous cell carcinoma

23 Dec 2018

Abstract excerpt

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is more prevalent in men than women and this disparity cannot be fully explained by known risk factors. Recent studies have shown that loss of Y chromosome (LoY) confers an increased risk of solid cancer and reduces life expectancy in men. METHODS: Using publicly available data from The Cancer Genome Atlas, we investigated the prevalence of LoY and its...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 30582241
DOI: 10.1002/hed.25537

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