Back to search

Article

S1P/HDAC1 Signaling Regulates Macrophage Polarization in Patients with Chronic Obstructive Pulmonary Disease

2021-07-28

Abstract excerpt

Throughout the world, chronic obstructive pulmonary disease (COPD) is the cause of substantial morbidity and mortality and represents a large public health burden. Previous studies reported that inflammation is intimately involved in COPD, but the underlying mechanism remains unclear. As macrophage polarization was demonstrated to regulate inflammation, we hypothesized that COPD alters macrophage polarization. To...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ba41f3af-e970-5216-9b11-4d110d14e3da
DOI
10.21203/rs.3.rs-743109/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
S1P/HDAC1 Signaling Regulates Macrophage Polarization in Patients with Chronic Obstructive Pulmonary DiseaseDOI 10.21203/rs.3.rs-743109/v1
Macrophage Polarization and Functions in Pathogenesis of Chronic Obstructive Pulmonary DiseaseSemantic proximity
Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary DiseaseSemantic proximity
Macrophage Polarization: An Important Candidate Regulator for Lung Diseases.Semantic proximity
Epigenetic regulation of macrophage activation in chronic obstructive pulmonary diseaseSemantic proximity
Targeting BRD4 Ameliorates Experimental Emphysema by Disrupting Super-Enhancer in Polarized Alveolar MacrophageSemantic proximity
Identification of Macrophage Polarization‐Related Genes as Biomarkers of Chronic Obstructive Pulmonary Disease Based on Bioinformatics AnalysesSemantic proximity
COPD Patients Exhibit Distinct Gene Expression, Accelerated Cellular Aging, and Bias to M2 MacrophagesSemantic proximity
Knockdown of RTEL1 Alleviates Chronic Obstructive Pulmonary Disease by Modulating M1, M2 Macrophage Polarization and InflammationSemantic proximity
The Crucial Role of the PPAR Signaling Pathway in the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease: An Analysis of Gene Expression and Macrophage Polarization.Semantic proximity
Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPDSemantic proximity
Molecular changes underlying pulmonary emphysema and chronic bronchitis in Chronic Obstructive Pulmonary Disease: An updated review.Semantic proximity
Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary diseaseSemantic proximity
Select a neighboring publication to make it the new centre.