Article

Neutrophil biomechanical properties and immune function in health and inflammatory disease

2021-01-01

Abstract excerpt

Low density granulocytes (LDGs) are a poorly understood class of immune cells found in patients with chronic inflammatory diseases including psoriasis and systemic lupus erythematosus (SLE). Research completed at the National Institutes of Health (NIH) revealed that in the context of SLE, LDGs release higher levels of type 1 interferons, undergo increased NETosis, and accordingly drive inflammation. Meanwhile, adv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ba41c49d-c035-53f8-bc1b-ac5bddc02158
DOI: 10.17863/cam.72572

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neutrophil biomechanical properties and immune function in health and inflammatory diseaseDOI 10.17863/cam.72572Read

Aging and interferon gamma response drive the phenotype of neutrophils in the inflamed jointSemantic proximity Read

The mechanics of myeloid cells.Semantic proximity Read

A prototypical phenotype for neutrophils in lupus: the potential contribution of immune complexesSemantic proximity Read

Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint.Semantic proximity Read

Neutrophil nucleus: shaping the past and the futureSemantic proximity Read

Different Faces for Different Places: Heterogeneity of Neutrophil Phenotype and FunctionSemantic proximity Read

Distinct Functional States of Neutrophils by Actin Disassembly and NF-kB/STAT3 SignalingSemantic proximity Read

Neutrophil activation signature in juvenile idiopathic arthritis indicates the presence of low-density granulocytesSemantic proximity Read

Complexity of the neutrophil transcriptome in early and severe rheumatoid arthritis: a role for microRNAs?Semantic proximity Read

Neutrophils, neutrophil extracellular traps, and rheumatoid arthritis: An updated review for cliniciansSemantic proximity Read

Complexity of the neutrophil transcriptome in early and severe rheumatoid arthritis. A role for microRNAs?Semantic proximity Read

Ultra-pure isolation of low density neutrophils casts doubt on their exceptionality in health and diseaseSemantic proximity Read