Article

Altered microglial plasticity in the periaqueductal grey of adolescent Mecp2-heterozygous mice following early-life stress

2025-04-21

Abstract excerpt

<title>Abstract</title> <p>Rett syndrome (RTT), a severe neurodevelopmental disorder primarily affecting girls, is commonly caused by <italic>MECP2</italic> loss-of-function mutations. Key symptoms include motor impairments, typical hand stereotypies and intellectual disability. Moreover, although not thoroughly studied, anxiety, heightened stress sensitivity, and aberrant pain perception are also an important co...

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Literature Corpus work: 9e96d4ea-7274-5bc1-a625-8d3567455916
DOI: 10.21203/rs.3.rs-6219388/v1

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