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GRWR Correlates with the Metabolism of Tacrolimus After Pediatric Living Donor Liver Transplantation Accorrding to Donor CYP3A5 Polymorphism

2022-02-15

Abstract excerpt

<h4>Objectives: </h4> Tacrolimus is characterized by high pharmacokinetic variability in combination with a narrow therapeutic range. However, influence of donor CYP3A5 genotype and graft-to-recipient body weight ratio (GRWR) on tacrolimus’ pharmacokinetics after pediatric living donor liver transplantation (LDLT) remains unclear. <h4>Methods: </h4>: A total of 174 LDLT recipients (<6y) were grouped according to d...

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Literature Corpus work
ba1fc951-530e-5039-af3b-5d6fe8c246d2
DOI
10.21203/rs.3.rs-1223012/v1
Open publication

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GRWR Correlates with the Metabolism of Tacrolimus After Pediatric Living Donor Liver Transplantation Accorrding to Donor CYP3A5 PolymorphismDOI 10.21203/rs.3.rs-1223012/v1
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