Article

MutaPhy: A clade-based framework to detect genotype-phenotype associations on phylogenetic trees

2026-04-21

Abstract excerpt

Understanding how genetic variation in pathogens influences clinical phenotypes observed in infected hosts is a fundamental challenge in evolutionary genomics and public health. Phenotypic traits such as infection severity are often non-randomly distributed within the pathogen's phylogeny, suggesting the existence of evolutionary determinants but also violating the independence assumption underlying classical geno...

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Literature Corpus work: b9df7e98-2fca-5bef-b2b7-236626df5cea
DOI: 10.64898/2026.04.19.719535

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