Article

A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombination

2017-05-22

Abstract excerpt

Genome-Wide Association Studies (GWAS) in microbial organisms have the potential to vastly improve the way we understand, manage, and treat infectious diseases. Yet, GWAS methods established thus far remain insufficiently able to capitalise on the growing wealth of bacterial and viral genetic sequence data. Facing clonal population structure and homologous recombination, existing GWAS methods struggle to achieve b...

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Literature Corpus work: 25455792-abab-59a3-bf7b-7bd4a4292aec
DOI: 10.1101/140798

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