Article

Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently

2018-12-13

Abstract excerpt

Earlier we showed that human genome contains many evolutionarily young or novel genes with tumor-specific or tumor-predominant expression. We suggested to call them TSEEN genes, i.e. T umor S pecifically E xpressed, E volutionarily N ew genes. In this paper we performed a study of the evolutionary ages of different classes of human genes, using homology searches in genomes of different taxa in human lineage....

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Literature Corpus work: b98e67cb-c63c-58dc-9ff6-b6db48c24a80
DOI: 10.1101/493627

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