Article

Tracing Evolutionary Ages of Cancer-Driving Sites by Cancer Somatic Mutations

2020-02-10

Abstract excerpt

Evolutionary understanding of cancer genes may provide insights on the nature and evolution of complex life and the origin of multicellularity. In this study, we focus on the evolutionary ages of cancer-driving sites, and try to explore to what extent the amino acids of cancer-driving sites can be traced back to the most recent common ancestor (MRCA) of the gene. According to gene phylostraigraphy analysis, we use...

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Literature Corpus work: 3b7a3d3e-a61b-5f95-9610-3ade02a1b840
DOI: 10.1101/2020.02.09.940528

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