Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New genes contribute to genetic and phenotypic novelties in human evolution.

Current opinion in genetics & development - 1 Dec 2014

Zhang Yong E, Long Manyuan

Abstract excerpt

New genes in human genomes have been found relevant in evolution and biology of humans. It was conservatively estimated that the human genome encodes more than 300 human-specific genes and 1000 primate-specific genes. These new arrivals appear to be implicated in brain function and male reproduction. Surprisingly, increasing evidence indicates that they may also bring negative pleiotropic effects, while assuming...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Evolution, Molecular
Share to Genetic Fitness

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Hominidae

Share to Phenotype

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25218862
DOI: 10.1016/j.gde.2014.08.013
PMCID: PMC4631527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New genes contribute to genetic and phenotypic novelties in human evolution.PMID 25218862Read ↗

New genes as drivers of phenotypic evolution.Semantic proximity Read ↗

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.Semantic proximity Read ↗

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.Semantic proximity Read ↗

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.Semantic proximity Read ↗

Novelty versus innovation of gene regulatory elements in human evolution and disease.Semantic proximity Read ↗

Understanding rare and common diseases in the context of human evolution.Semantic proximity Read ↗

De novo origin of human protein-coding genes.Semantic proximity Read ↗

Human Evolutionary Genetics: Origins, Peoples and Disease.Semantic proximity Read ↗

Evolution of genetic and genomic features unique to the human lineage.Semantic proximity Read ↗

Human Evolutionary Genetics: Origins, Peoples & DiseaseSemantic proximity Read ↗

Human brain evolution: from gene discovery to phenotype discovery.Semantic proximity Read ↗

Exploring the potential relevance of human-specific genes to complex disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.