Article

Merkel cell polyomavirus infection and persistence modelled in skin organoids

2025-02-12

Abstract excerpt

Merkel cell polyomavirus (MCPyV) causes most Merkel cell carcinomas (MCC). The virus is one of the few known human tumor viruses, and due to its direct role in this skin cancer development, it is a bona fide model for viral tumorigenesis and tumorigenesis in general. Chronic viruses in humans such as MCPyV are highly adapted to their host and current models to study infection, persistence and pathogenesis are high...

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Literature Corpus work: b9610015-1fdd-5fc1-ad12-62b1f5501793
DOI: 10.1101/2025.02.11.637697

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