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Characterization of the Impact of Merkel Cell Polyomavirus-Induced Interferon Signaling on Viral Infection

22 Mar 2023

Abstract excerpt

Merkel cell carcinoma is an aggressive skin cancer that is particularly lethal to immunocompromised individuals. Though rare, MCC incidence has increased significantly in recent years. There are no lasting and effective treatments for metastatic disease, highlighting the need for additional treatment and prevention strategies. By investigating how the host innate immune system interfaces with Merkel cell...

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PMID: 36946735
DOI: 10.1128/jvi.01907-22

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