Article

ATF3-SLC7A7 Axis Regulates mTORC1 Signaling to Suppress Lipogenesis and Tumorigenesis in Hepatocellular Carcinoma

2024-10-07

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) remains a major global health challenge with poor prognosis and high mortality. Dysregulated lipid metabolism is increasingly recognized as a key driver of HCC progression. While the transcription factor ATF3 has been implicated in tumorigenesis and lipid regulation, its precise role in HCC development and lipid biosynthesis is not fully unders...

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Literature Corpus work: b9133ddf-ed1b-5c69-bd8e-186092df0d77
DOI: 10.21203/rs.3.rs-5195664/v1

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