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Article

PERK/ATF4/LAMP3-arm contributes to the aggressive phenotype of hepatocellular carcinoma cells in response to the chronic ethanol exposure.

Scientific reports - 25 Jan 2026

Goyal Himanshi, Kaur Jyotdeep

Abstract excerpt

Hepatocellular carcinoma (HCC), the predominant form of liver cancer, is the fifth most prevalent cancer worldwide and second leading cause of cancer-related deaths, underscoring its grim prognosis. Key risk factors for HCC include HBV, HCV, cirrhosis, inherited metabolic diseases, vitamin supplementation, heavy alcohol use, obesity etc. Despite the well-documented impact of alcohol on HCC, there remains a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41582194
DOI: 10.1038/s41598-026-37114-9
PMCID: PMC12905446

Genes

ATF4
LAMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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