Article

Antisense transcription-dependent chromatin signature modulates sense transcription and transcript dynamics

2017-09-11

Abstract excerpt

Antisense transcription is widespread in genomes. Despite large differences in gene size and architecture, we find that yeast and human genes share a unique, antisense transcription-associated chromatin signature. We asked whether this signature is related to a biological function for antisense transcription. Using quantitative RNA-FISH, we observed changes in sense transcript distributions in nuclei and cytoplasm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b90c8d86-2e43-5722-8b03-3975cc4adf64
DOI: 10.1101/187237

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antisense transcription-dependent chromatin signature modulates sense transcription and transcript dynamicsDOI 10.1101/187237Read

Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing.Semantic proximity Read

Direct long-read RNA sequencing uncovers functional variation affecting transcript production and RNA modificationsSemantic proximity Read

Direct long-read RNA sequencing uncovers functional variation affecting transcript production and RNA modificationsSemantic proximity Read

Protein-coding cis-natural antisense transcripts have high and broad expression in Arabidopsis.Semantic proximity Read

Stereoscopic RNA Analysis of Transcriptional and Post-transcriptional RegulationSemantic proximity Read

ATP-dependent chromatin remodeling shapes the long noncoding RNA landscape.Semantic proximity Read

Natural antisense transcripts: sound or silence?Semantic proximity Read

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic diseaseSemantic proximity Read

Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repressionSemantic proximity Read

Alternative polyadenylation mediates genetic regulation of gene expressionSemantic proximity Read

Alternative applications for distinct RNA sequencing strategies.Semantic proximity Read

Size selected NET‐Seq reveals a conserved architecture of transcription units around yeast genes.Semantic proximity Read